Article
Donor CTLA-4 Genotype Modulates the Immune Response to Minor Histocompatibility Antigen Mismatches.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Dec 2017
Gallardo David, Bosch-Vizcaya Anna, Rodríguez-Romanos Rocío, Santos Nazly, Buño Ismael, de la Cámara Rafael, Brunet Salut, Jiménez-Velasco Antonio, González Marcos, Nieto Jose B, Martínez-Laperche Carolina, Vallejo Carlos, Ferrá Christelle, Sampol Antònia, López-Jiménez Javier, Pérez-Simón Jose A, Martínez Carmen, Díez Jose L
Abstract excerpt
Minor histocompatibility antigen (miHA) mismatches have been related to graft-versus-host disease (GVHD) after allogeneic stem cell transplantation, but this association remains controversial due to the lack of consistency in the results obtained by different groups. The CTLA-4 genotype of the donor has been reported to be relevant in the appearance of acute GVHD. We explored the effect of the donor's CTLA-4...
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