Article
Identification and Characterization of Multiple TRIM Proteins That Inhibit Hepatitis B Virus Transcription
1 Aug 2013
Abstract excerpt
Tripartite motif (TRIM) proteins constitute a family of over 100 members that share conserved tripartite motifs and exhibit diverse biological functions. Several TRIM proteins have been shown to restrict viral infections and regulate host cellular innate immune responses. In order to identify TRIM proteins that modulate the infection of hepatitis B virus (HBV), we tested 38 human TRIMs for their effects on HBV...
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