Article
Suppression of interferon-mediated anti-HBV response by single CpG methylation in the 5′-UTR of TRIM22
23 Mar 2017
Abstract excerpt
Objective Interferons (IFNs) mediate direct antiviral activity. They play a crucial role in the early host immune response against viral infections. However, IFN therapy for HBV infection is less effective than for other viral infections. Design We explored the cellular targets of HBV in response to IFNs using proteome-wide screening. Results Using LC-MS/MS, we identified proteins downregulated and upregulated by...
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