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Article

TRIM22. A Multitasking Antiviral Factor

23 Jul 2021

Abstract excerpt

Viral invasion of target cells triggers an immediate intracellular host defense system aimed at preventing further propagation of the virus. Viral genomes or early products of viral replication are sensed by a number of pattern recognition receptors, leading to the synthesis and production of type I interferons (IFNs) that, in turn, activate a cascade of IFN-stimulated genes (ISGs) with antiviral functions. Among...

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PMID: 34440633
DOI: 10.3390/cells10081864

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