Article
Association between chronic hepatitis B virus infection and HLA-DP gene polymorphisms in the Turkish population.
Virus research - 15 Mar 2017
Akgöllü Ersin, Bilgin Ramazan, Akkız Hikmet, Ülger Yakup, Kaya Berrin Yalınbaş, Karaoğullarından Ümit, Arslan Yusuf Kemal
Abstract excerpt
AIM: Hepatitis B virus (HBV) affects approximately 360 million people worldwide. 10-15% of patients with chronic HBV develop liver cirrhosis (LC), liver failure and hepatocellular carcinoma (HCC). Chronic HBV infection or HBV clearance is influenced by both viral and host factors. In genome-wide association studies (GWAS), the human leukocyte antigen (HLA) gene polymorphisms rs3077 and rs9277535 were identified...
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