Article
Detection of Driver Modules with Rarely Mutated Genes in Cancers.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Li Feng, Gao Lin, Wang Bingbo
Abstract excerpt
Identifying driver modules or pathways is a key challenge to interpret the molecular mechanisms and pathogenesis underlying cancer. An increasing number of studies suggest that rarely mutated genes are important for the development of cancer. However, the driver modules consisting of mutated genes with low-frequency driver mutations are not well characterized. To identify driver modules with rarely mutated genes,...
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