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Article

Statistical tests for detecting variance effects in quantitative trait studies.

Bioinformatics (Oxford, England) - 15 Jan 2019

Dumitrascu Bianca, Darnell Gregory, Ayroles Julien, Engelhardt Barbara E

Abstract excerpt

Motivation: Identifying variants, both discrete and continuous, that are associated with quantitative traits, or QTs, is the primary focus of quantitative genetics. Most current methods are limited to identifying mean effects, or associations between genotype or covariates and the mean value of a quantitative trait. It is possible, however, that a variant may affect the variance of the quantitative trait in lieu...

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Identifiers

PMID: 29982387
DOI: 10.1093/bioinformatics/bty565
PMCID: PMC6330007

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