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Article

The RNA-Binding Protein Scp160p Facilitates Aggregation of Many Endogenous Q/N-Rich Proteins.

Cell reports - 3 Jul 2018

Cheng Matthew H K, Hoffmann Patrick C, Franz-Wachtel Mirita, Sparn Carola, Seng Charlotte, Maček Boris, Jansen Ralf-Peter

Abstract excerpt

The RNA-binding protein Scp160p is the yeast homolog of the conserved vigilin protein family. These proteins influence a variety of nuclear and cytoplasmic functions. One of Scp160p's reported roles is to increase translation elongation efficiency in a manner related to codon usage. Thus, it can affect translation speed and co-translational folding of nascent peptides. We used polyglutamine (polyQ) reporters to...

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Identifiers

PMID: 29972781
DOI: 10.1016/j.celrep.2018.06.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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