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Article

Bias in Mendelian randomization due to assortative mating.

Genetic epidemiology - 1 Oct 2018

Hartwig Fernando Pires, Davies Neil Martin, Davey Smith George

Abstract excerpt

Mendelian randomization (MR) has been increasingly used to strengthen causal inference in observational epidemiology. Methodological developments in the field allow detecting and/or adjusting for different potential sources of bias, mainly bias due to horizontal pleiotropy (or "off-target" genetic effects). Another potential source of bias is nonrandom matching between spouses (i.e., assortative mating). In this...

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Identifiers

PMID: 29971821
DOI: 10.1002/gepi.22138
PMCID: PMC6221130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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