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Article

A genetic variant located in the miR-532-5p-binding site of TGFBR1 is associated with the colorectal cancer risk.

Journal of gastroenterology - 1 Feb 2019

Gu Dongying, Li Shuwei, Du Mulong, Tang Cuiju, Chu Haiyan, Tong Na, Zhang Zhengdong, Wang Meilin, Chen Jinfei

Abstract excerpt

BACKGROUND: Genome-wide association studies have identified genes in the transforming growth factor-β (TGFβ) signaling pathway that are responsible for regulating carcinogenesis. METHODS: We searched for single-nucleotide polymorphisms (SNPs) located within 3'-untranslated regions (3'-UTRs) that might affect the ability of miRNAs to bind genes in the TGFβ pathway for further analysis. We used TaqMan technology to...

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Source

Identifiers

PMID: 29971498
DOI: 10.1007/s00535-018-1490-y

Genes

TGFBR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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