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Article

c.29C>T polymorphism in the transforming growth factor-β1 (TGFB1) gene correlates with increased risk of urinary bladder cancer.

Cytokine - 1 Oct 2015

Gautam Kirti Amresh, Pooja Singh, Sankhwar Satya Narayan, Sankhwar Pushp Lata, Goel Apul, Rajender Singh

Abstract excerpt

TGF-β1 is a pleiotropic cytokine, which plays a dual role in tumor development. In the early stages, it inhibits the growth of tumor while in the late stages of carcinoma, it promotes tumor growth. The purpose of this study was to analyze the distribution of the TGFB1 gene polymorphisms between cases and controls so as to assess their correlation with bladder cancer risk. This study included 237 cases of urinary...

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Identifiers

PMID: 26048435
DOI: 10.1016/j.cyto.2015.05.017

Genes

TGFB1

Variants

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