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Article

Genetic variations in the TGFβ signaling pathway, smoking and risk of colorectal cancer in a Chinese population.

Carcinogenesis - 1 Apr 2013

Zhong Rong, Liu Li, Zou Li, Sheng Wei, Zhu Beibei, Xiang Hao, Chen Wei, Chen Jigui, Rui Rui, Zheng Xiawen, Yin Jieyun, Duan Shengyu, Yang Beifang, Sun Jingwen, Lou Jiao, Liu Li, Xie Duoshuang, Xu Yihua, Nie Shaofa, Miao Xiaoping

Abstract excerpt

Recent genome-wide association studies (GWAS) have reported multiple risk loci associated with risk of colorectal cancer (CRC), some of which are involved in the transforming growth factor beta (TGFβ) signaling pathway. We systematically examined associations of common genetic variations in the TGFβ signaling pathway and environmental factors with CRC risk using a two-staged case-control study in a Chinese...

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Source

Identifiers

PMID: 23275154
DOI: 10.1093/carcin/bgs395

Genes

SMAD7
TGFBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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