Article
Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma
18 Jun 2018
Abstract excerpt
Metabolic reprogramming is a hallmark of many cancer types, including hepatocellular carcinoma (HCC). Identifying the critical players in this process might be crucial for the generation of novel and effective anti-neoplastic therapies. In the present investigation, we determined the importance of carbohydrate responsive element binding protein (ChREBP), a central player in the regulation of lipid and glucose...
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