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Clinical Characteristics, Molecular Analysis and Survival Outcomes of Patients With Extramedullary Acute Myeloid Leukemia: A Retrospective Single-Center Study.

Clinical lymphoma, myeloma & leukemia - 1 Apr 2026

Song Jingyu, Lv Xiaoli, Li Qi, Zhao Yanqiu, Guo Dan, Liu Jie, Ding Peiwen, Ji Jiajuan, Zhu Yuting, Luo Dan, Li Huibo, Fan Shengjin

Abstract excerpt

BACKGROUND: Extramedullary acute myeloid leukemia (eAML) is a rare subtype of AML. The clinical features, molecular mechanisms and prognosis of eAML remain controversial. This study aimed to systematically analyze the differences in clinical and molecular characteristics between eAML patients and AML patients, and evaluate the impact of this disease subtype on survival outcomes. METHODS: We retrospectively...

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Aged
DNMT3A gene
Leukemia, Myeloid, Acute
Mutation
Nucleophosmin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Survival Analysis

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Identifiers

PMID: 41580336
DOI: 10.1016/j.clml.2025.12.011

Genes

ASXL1
DNMT3A
KMT2A
KRAS
NPM1
PTPN11
TET2
U2AF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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