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Article

C.B-17 SCID mice develop epicardial calcinosis with unaltered cardiac function.

Fundamental & clinical pharmacology - 1 Feb 2019

Raghunathan Suchi, Reynolds Corey L, Schwartz Robert J, Stewart M David, McConnell Bradley K

Abstract excerpt

Inbred mouse strains are the most widely used mammalian model organism in biomedical research owing to ease of genetic manipulation and short lifespan; however, each inbred strain possesses a unique repertoire of deleterious homozygous alleles that can make a specific strain more susceptible to a particular disease. In the current study, we report dystrophic cardiac calcinosis (DCC) in C.B-17 SCID male mice at 10...

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Source

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Identifiers

PMID: 29959870
DOI: 10.1111/fcp.12398
PMCID: PMC6311438

Genes

DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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