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Article

Mouse genome-wide association study identifies polymorphisms on chromosomes 4, 11, and 15 for age-related cardiac fibrosis.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2016

Li Qiaoli, Berndt Annerose, Sundberg Beth A, Silva Kathleen A, Kennedy Victoria E, Cario Clinton L, Richardson Matthew A, Chase Thomas H, Schofield Paul N, Uitto Jouni, Sundberg John P

Abstract excerpt

Dystrophic cardiac calcinosis (DCC), also called epicardial and myocardial fibrosis and mineralization, has been detected in mice of a number of laboratory inbred strains, most commonly C3H/HeJ and DBA/2J. In previous mouse breeding studies between these DCC susceptible and the DCC-resistant strain C57BL/6J, 4 genetic loci harboring genes involved in DCC inheritance were identified and subsequently termed Dyscalc...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27126641
DOI: 10.1007/s00335-016-9634-y
PMCID: PMC5235362

Genes

DCC

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