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Article

A locus on chromosome 7 determines myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice.

Proceedings of the National Academy of Sciences of the United States of America - 28 May 1996

Ivandic B T, Qiao J H, Machleder D, Liao F, Drake T A, Lusis A J

Abstract excerpt

Dystrophic cardiac calcinosis, an age-related cardiomyopathy that occurs among certain inbred strains of mice, involves myocardial injury, necrosis, and calcification. Using a complete linkage map approach and quantitative trait locus analysis, we sought to identify genetic loci determining dystrophic cardiac calcinosis in an F2 intercross of resistant C57BL/6J and susceptible C3H/HeJ inbred strains. We...

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Identifiers

PMID: 8643601
DOI: 10.1073/pnas.93.11.5483
PMCID: PMC39272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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