Gap junctions and the connexin protein family.

doi:10.1016/j.cardiores.2003.11.013

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Article

Gap junctions and the connexin protein family.

Cardiovascular research - 1 May 2004

Söhl Goran, Willecke Klaus

Abstract excerpt

Gap junctions (Gj) form conduits between adjacent cells that are composed of connexin (Cx) protein subunits and allow direct intercellular communication. To date, the connexin gene family comprises 20 members in the mouse and 21 members in the human genome, 19 of which can be grouped as sequence-orthologous pairs. The structure of connexin genes is relatively simple. An untranslated exon 1 is separated by an...

Topics

Animals
Cell Communication
Connexins
Endothelial Cells
Endothelium, Vascular
Gap Junctions
Humans
Mice
Mutation
Myocytes, Cardiac
Protein Structure, Tertiary

Source

Open in PubMed

Identifiers

PMID: 15094343
DOI: 10.1016/j.cardiores.2003.11.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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