Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endothelial Connexin37 and Connexin40 participate in basal but not agonist-induced NO release.

Cell communication and signaling : CCS - 22 Jul 2015

Meens Merlijn J, Alonso Florian, Le Gal Loïc, Kwak Brenda R, Haefliger Jacques-Antoine

Abstract excerpt

BACKGROUND: Connexin37 (Cx37) and Cx40 are crucial for endothelial cell-cell communication and homeostasis. Both connexins interact with endothelial nitric oxide synthase (eNOS). The exact contribution of these interactions to the regulation of vascular tone is unknown. RESULTS: Cx37 and Cx40 were expressed in close proximity to eNOS at cell-cell interfaces of mouse aortic endothelial cells. Absence of Cx37 did...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcholine
Share to Aorta
Share to Endothelium, Vascular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gap Junction alpha-5 Protein

Share to Nitric Oxide

Share to Nitric Oxide Synthase Type III

Share to Vasoconstriction

Share to Vasodilation

Source

Open in PubMed Open full text

Identifiers

PMID: 26198171
DOI: 10.1186/s12964-015-0110-1
PMCID: PMC4510910

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endothelial Connexin37 and Connexin40 participate in basal but not agonist-induced NO release.PMID 26198171Read ↗

Defective Cx40 Maintains Cx37 Expression but Intact Cx40 Is Crucial for Conducted Dilations Irrespective of HypertensionSemantic proximity Read ↗

Connexins: Key Players in the Control of Vascular Plasticity and Function.Semantic proximity Read ↗

Lack of vascular connexin 40 is associated with hypertension and irregular arteriolar vasomotion.Semantic proximity Read ↗

Connexin 43 Plays a Role in Pulmonary Vascular Reactivity in Mice.Semantic proximity Read ↗

Gap Junction Protein Cx37 Interacts With Endothelial Nitric Oxide Synthase in Endothelial CellsSemantic proximity Read ↗

Replacement of connexin 43 by connexin 32 in a knock-in mice model attenuates aortic endothelium-derived hyperpolarizing factor-mediated relaxation.Semantic proximity Read ↗

Gap junctions and the connexin protein family.Semantic proximity Read ↗

Loss of functional endothelial connexin40 results in exercise-induced hypertension in mice.Semantic proximity Read ↗

Connexin37: a potential modifier gene of inflammatory disease.Semantic proximity Read ↗

Critical Role of Cx40 in Reduced Endothelial Electrical Coupling by Lipopolysaccharide and Hypoxia-Reoxygenation.Semantic proximity Read ↗

Targeting Cx40 (Connexin40) Expression or Function Reduces Angiogenesis in the Developing Mouse Retina.Semantic proximity Read ↗

Nitric oxide lacks direct effect on TRPC5 channels but suppresses endogenous TRPC5-containing channels in endothelial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.