Connexins: Key Players in the Control of Vascular Plasticity and Function.

Abstract excerpt

Of the 21 members of the connexin family, 4 (Cx37, Cx40, Cx43, and Cx45) are expressed in the endothelium and/or smooth muscle of intact blood vessels to a variable and dynamically regulated degree. Full-length connexins oligomerize and form channel structures connecting the cytosol of adjacent cells (gap junctions) or the cytosol with the extracellular space (hemichannels). The different connexins vary mainly...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blood Vessels
• Share to Capillary Permeability
• Share to Cell Plasticity