Article
Genotyping performance evaluation of commercially available HIV-1 drug resistance test.
PloS one - 1 Jan 2018
Rosemary Audu, Chika Onwuamah, Jonathan Okpokwu, Godwin Imade, Georgina Odaibo, Azuka Okwuraiwe, Zaidat Musa, Philippe Chebu, Oliver Ezechi, Oche Agbaji, David Olaleye, Jay Samuel, Ibrahim Dalhatu, Mukhtar Ahmed, Joshua DeVos, Chunfu Yang, Elliot Raizes, Beth Chaplin, Phyllis Kanki, Emmanuel Idigbe
Abstract excerpt
BACKGROUND: ATCC HIV-1 drug resistance test kit was designed to detect HIV-1 drug resistance (HIVDR) mutations in the protease and reverse transcriptase genes for all HIV-1 group M subtypes and circulating recombinant forms. The test has been validated for both plasma and dried blood spot specimen types with viral load (VL) of ≥1000 copies/ml. We performed an in-country assessment on the kit to determine the...
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