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Article

A scalable estimator of SNP heritability for biobank-scale data.

Bioinformatics (Oxford, England) - 1 Jul 2018

Wu Yue, Sankararaman Sriram

Abstract excerpt

Motivation: Heritability, the proportion of variation in a trait that can be explained by genetic variation, is an important parameter in efforts to understand the genetic architecture of complex phenotypes as well as in the design and interpretation of genome-wide association studies. Attempts to understand the heritability of complex phenotypes attributable to genome-wide single nucleotide polymorphism (SNP)...

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PMID: 29950019
DOI: 10.1093/bioinformatics/bty253
PMCID: PMC6022682

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