Article
Scalable summary-statistics-based heritability estimation method with individual genotype level accuracy.
Genome research - 11 Oct 2024
Jeong Moonseong, Pazokitoroudi Ali, Liu Zhengtong, Sankararaman Sriram
Abstract excerpt
SNP heritability, the proportion of phenotypic variation explained by genotyped SNPs, is an important parameter in understanding the genetic architecture underlying various diseases and traits. Methods that aim to estimate SNP heritability from individual genotype and phenotype data are limited by their ability to scale to Biobank-scale data sets and by the restrictions in access to individual-level data. These...
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