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Fast heritability estimation based on MINQUE and batch training.

Briefings in bioinformatics - 13 May 2022

Tang Mingsheng, Hou Tingting, Tong Xiaoran, Shen Xiaoxi, Zhang Xuefen, Wang Tong, Lu Qing

Abstract excerpt

Heritability, the proportion of phenotypic variance explained by genome-wide single nucleotide polymorphisms (SNPs) in unrelated individuals, is an important measure of the genetic contribution to human diseases and plays a critical role in studying the genetic architecture of human diseases. Linear mixed model (LMM) has been widely used for SNP heritability estimation, where variance component parameters are...

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PMID: 35383355
DOI: 10.1093/bib/bbac115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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