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Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets

26 Jun 2018

Abstract excerpt

In patients with asthma or chronic obstructive pulmonary disease, rhinovirus (RV) infections can provoke acute worsening of disease, and limited treatment options exist. Viral replication in the host cell induces significant remodeling of intracellular membranes, but few studies have explored this mechanistically or as a therapeutic opportunity. We performed unbiased lipidomic analysis on human bronchial...

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PMID: 29946055
DOI: 10.1194/jlr.m085910

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