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A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants

2022-02-15

Abstract excerpt

A comprehensive understanding of host dependency factors for SARS-CoV-2 remains elusive. We mapped alterations in host lipids following SARS-CoV-2 infection using nontargeted lipidomics. We found that SARS-CoV-2 rewires host lipid metabolism, altering 409 lipid species up to 64-fold relative to controls. We correlated these changes with viral protein activity by transfecting human cells with each viral protein and...

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Identifiers and source

Literature Corpus work
172051ba-7890-55ad-81c5-bdabf8aa09eb
DOI
10.1101/2022.02.14.480430
Open publication

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A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variantsDOI 10.1101/2022.02.14.480430
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