Article
Long-Term In Vitro Culture of the Syphilis Spirochete Treponema pallidum subsp. pallidum
25 Jun 2018
Abstract excerpt
ABSTRACT Investigation of Treponema pallidum subsp. pallidum , the spirochete that causes syphilis, has been hindered by an inability to culture the organism continuously in vitro despite more than a century of effort. In this study, long-term logarithmic multiplication of T. pallidum was attained through subculture every 6 to 7 days and periodic feeding using a modified medium ( T. pallidum culture medium 2...
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