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Article

In Vitro Cultivation of the Syphilis Spirochete Treponema pallidum

1 Feb 2021

Abstract excerpt

For over a century, investigation of Treponema pallidum subsp. pallidum, the spiral-shaped bacterium that causes syphilis, was hindered by an inability to culture the organism in vitro. A recent breakthrough has enabled continuous in vitro growth of this organism in co-culture with mammalian tissue culture cells. This article contains the protocols needed to culture T. pallidum in the standard laboratory...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33599121
DOI: 10.1002/cpz1.44

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