Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Natural Killer T Cells in the Development of Obesity and Insulin Resistance: Insights From Recent Progress

11 Jun 2018

Abstract excerpt

Natural killer T (NKT) cells play important roles in adipose tissue inflammation, and thus influence the development of diet-induced obesity and insulin resistance. The interactions between cluster of differentiation (CD)1d and NKT T cell receptor are thought to be critical in this process, as demonstrated in two NKT cell-deficient mouse models-systemic CD1d gene knockout (KO) and prototypic Jα18 KO mice. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29942311
DOI: 10.3389/fimmu.2018.01314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Natural Killer T Cells in the Development of Obesity and Insulin Resistance: Insights From Recent ProgressPMID 29942311Read ↗

Tissue-Specific Phenotype and Activation of iNKT Cells in Morbidly Obese Subjects: Interaction with Adipocytes and Effect of Bariatric Surgery.Semantic proximity Read ↗

iNKT and MAIT Cell Alterations in DiabetesSemantic proximity Read ↗

A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease.Semantic proximity Read ↗

Impact of CD1d deficiency on metabolism.Semantic proximity Read ↗

Natural killer T cells in lipoprotein metabolism and atherosclerosis.Semantic proximity Read ↗

Phenotypic diversity of human adipose tissue-resident NK cells in obesity.Semantic proximity Read ↗

MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes.Semantic proximity Read ↗

Deciphering visceral adipose tissue regulatory T cells: Key contributors to metabolic healthSemantic proximity Read ↗

Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity.Semantic proximity Read ↗

Lipid accumulation in adipose tissue-resident iNKT cells contributes to an inflammatory phenotype.Semantic proximity Read ↗

<i>Apolipoprotein E</i> reduces the number and activation of non-invariant Natural Killer T cellsSemantic proximity Read ↗

A Subset of CD8αβ+ Invariant NKT Cells in a Humanized Mouse Model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.