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Article

Phenotypic diversity of human adipose tissue-resident NK cells in obesity.

Frontiers in immunology - 1 Jan 2023

Haugstøyl Martha E, Cornillet Martin, Strand Kristina, Stiglund Natalie, Sun Dan, Lawrence-Archer Laurence, Hjellestad Iren D, Busch Christian, Mellgren Gunnar, Björkström Niklas K, Fernø Johan

Abstract excerpt

Natural killer (NK) cells have emerged as key mediators of obesity-related adipose tissue inflammation. However, the phenotype of NK cell subsets residing in human adipose tissue are poorly defined, preventing a detailed understanding of their role in metabolic disorders. In this study, we applied multicolor flow cytometry to characterize CD56bright and CD56dim NK cells in blood and adipose tissue depots in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36911659
DOI: 10.3389/fimmu.2023.1130370
PMCID: PMC9996326

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