Tissue-Specific Phenotype and Activation of iNKT Cells in Morbidly Obese Subjects: Interaction with Adipocytes and Effect of Bariatric Surgery.

doi:10.1007/s11695-018-3215-y

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Tissue-Specific Phenotype and Activation of iNKT Cells in Morbidly Obese Subjects: Interaction with Adipocytes and Effect of Bariatric Surgery.

Obesity surgery - 1 Sept 2018

López Soledad, García-Serrano Sara, Gutierrez-Repiso Carolina, Rodríguez-Pacheco Francisca, Ho-Plagaro Ailec, Santiago-Fernandez Concepción, Alba Gonzalo, Cejudo-Guillen Marta, Rodríguez-Cañete Alberto, Valdes Sergio, Garrido-Sanchez Lourdes, Pozo David, García-Fuentes Eduardo

Abstract excerpt

BACKGROUND: The immune response of visceral adipose tissue (VAT) in obesity, in particular the role of invariant natural killer T (iNKT) cells, has not yet been fully elucidated. OBJECTIVE: To characterize iNKT cells and its activation status in VAT and peripheral blood mononuclear cells (PBMC) in morbidly obese subjects (MO), and to analyze their association with metabolic parameters. SUBJECTS AND METHODS:...

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Tissue-Specific Phenotype and Activation of iNKT Cells in Morbidly Obese Subjects: Interaction with Adipocytes and Effect of Bariatric Surgery.

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