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Article

Exome-chip association analysis reveals an Asian-specific missense variant in PAX4 associated with type 2 diabetes in Chinese individuals.

Diabetologia - 1 Jan 2017

Cheung Chloe Y Y, Tang Clara S, Xu Aimin, Lee Chi-Ho, Au Ka-Wing, Xu Lin, Fong Carol H Y, Kwok Kelvin H M, Chow Wing-Sun, Woo Yu-Cho, Yuen Michele M A, Hai JoJo S H, Jin Ya-Li, Cheung Bernard M Y, Tan Kathryn C B, Cherny Stacey S, Zhu Feng, Zhu Tong, Thomas G Neil, Cheng Kar-Keung, Jiang Chao-Qiang, Lam Tai-Hing, Tse Hung-Fat, Sham Pak-Chung, Lam Karen S L

Abstract excerpt

AIMS/HYPOTHESIS: Genome-wide association studies (GWASs) have identified many common type 2 diabetes-associated variants, mostly at the intronic or intergenic regions. Recent advancements of exome-array genotyping platforms have opened up a novel means for detecting the associations of low-frequency or rare coding variants with type 2 diabetes. We conducted an exomechip association analysis to identify additional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27744525
DOI: 10.1007/s00125-016-4132-z

Genes

PAX4
KCNQ1

Variants

rs2233580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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