Article
A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese.
PLoS genetics - 19 Feb 2010
Tsai Fuu-Jen, Yang Chi-Fan, Chen Ching-Chu, Chuang Lee-Ming, Lu Chieh-Hsiang, Chang Chwen-Tzuei, Wang Tzu-Yuan, Chen Rong-Hsing, Shiu Chiung-Fang, Liu Yi-Min, Chang Chih-Chun, Chen Pei, Chen Chien-Hsiun, Fann Cathy S J, Chen Yuan-Tsong, Wu Jer-Yuarn
Abstract excerpt
To investigate the underlying mechanisms of T2D pathogenesis, we looked for diabetes susceptibility genes that increase the risk of type 2 diabetes (T2D) in a Han Chinese population. A two-stage genome-wide association (GWA) study was conducted, in which 995 patients and 894 controls were genotyped using the Illumina HumanHap550-Duo BeadChip for the first genome scan stage. This was further replicated in 1,803...
Topics
Join the communities discussing this publication.