Article
Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.
Diabetologia - 1 Jun 2013
Ma R C W, Hu C, Tam C H, Zhang R, Kwan P, Leung T F, Thomas G N, Go M J, Hara K, Sim X, Ho J S K, Wang C, Li H, Lu L, Wang Y, Li J W, Wang Y, Lam V K L, Wang J, Yu W, Kim Y J, Ng D P, Fujita H, Panoutsopoulou K, Day-Williams A G, Lee H M, Ng A C W, Fang Y-J, Kong A P S, Jiang F, Ma X, Hou X, Tang S, Lu J, Yamauchi T, Tsui S K W, Woo J, Leung P C, Zhang X, Tang N L S, Sy H Y, Liu J, Wong T Y, Lee J Y, Maeda S, Xu G, Cherny S S, Chan T F, Ng M C Y, Xiang K, Morris A P, Keildson S, Hu R, Ji L, Lin X, Cho Y S, Kadowaki T, Tai E S, Zeggini E, McCarthy M I, Hon K L, Baum L, Tomlinson B, So W Y, Bao Y, Chan J C N, Jia W
Abstract excerpt
AIMS/HYPOTHESIS: Most genetic variants identified for type 2 diabetes have been discovered in European populations. We performed genome-wide association studies (GWAS) in a Chinese population with the aim of identifying novel variants for type 2 diabetes in Asians. METHODS: We performed a meta-analysis of three GWAS comprising 684 patients with type 2 diabetes and 955 controls of Southern Han Chinese descent. We...
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