Article
Common variants in KCNQ1 confer increased risk of type 2 diabetes and contribute to the diabetic epidemic in East Asians: a replication and meta-analysis.
Annals of human genetics - 1 Sept 2013
Wang Haoran, Miao Kun, Zhao Jinzhao, Liu Lei, Cui Guanglin, Chen Chen, Wang Dao Wen, Ding Hu
Abstract excerpt
We aimed to evaluate the effect of four common variants (rs2237892, rs2283228, rs2237895, and rs2237897) in KCNQ1 on susceptibility of type 2 diabetes (T2D) by performing a case-control study as well as a comprehensive meta-analysis. We genotyped these four variants in two sets of Chinese Han population, comprising a total of 2533 type 2 diabetic patients and 2643 nondiabetic controls. We also performed a...
Read the complete abstract on PubMed