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Article

Base Excision Repair Gene Polymorphisms and Wilms Tumor Susceptibility.

EBioMedicine - 1 Jul 2018

Zhu Jinhong, Jia Wei, Wu Caixia, Fu Wen, Xia Huimin, Liu Guochang, He Jing

Abstract excerpt

Base excision repair (BER) is the main mechanism to repair endogenous DNA lesions caused by reactive oxygen species. BER deficiency is linked with cancer susceptibility and premature aging. Single nucleotide polymorphisms (SNPs) within BER genes have been implicated in various human malignancies. Nevertheless, a comprehensive investigation of their association with Wilms tumor susceptibility is lacking. In this...

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Identifiers

PMID: 29937070
DOI: 10.1016/j.ebiom.2018.06.018
PMCID: PMC6085508

Genes

FEN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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