Article
Genetic variations in base excision repair pathway and risk of bladder cancer: a case-control study in the United States.
Molecular carcinogenesis - 1 Jan 2015
Xie Hui, Gong Yilei, Dai Jingyao, Wu Xifeng, Gu Jian
Abstract excerpt
Base excision repair (BER) is one of the major cellular DNA repair pathways that repairs small isolated foci of DNA damage including reduced or oxidized single bases or fragments and small, non-bulky adducts. Genetic variations in BER genes may affect DNA repair capacity and increase susceptibility to bladder cancer. In a case-control study of 801 bladder cancer patients and 801 matched controls, we evaluated the...
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