Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility.

Journal of the National Cancer Institute - 7 Jan 2009

Vineis Paolo, Manuguerra Maurizio, Kavvoura Fotini K, Guarrera Simonetta, Allione Alessandra, Rosa Fabio, Di Gregorio Alessandra, Polidoro Silvia, Saletta Federica, Ioannidis John P A, Matullo Giuseppe

Abstract excerpt

BACKGROUND: Several genes encoding for DNA repair molecules implicated in maintaining genomic integrity have been proposed as cancer-susceptibility genes. Although efforts have been made to create synopses for specific fields that summarize the data from genetic association studies, such an overview is not available for genes involved in DNA repair. METHODS: We have created a regularly updated database of studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bias
Share to DNA Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Mutation

Share to Neoplasms

Share to Odds Ratio

Share to Penetrance

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 19116388
DOI: 10.1093/jnci/djn437

Genes

ERCC2
XRCC1
XRCC2
BRCA2
CCND1
ERCC1
ERCC4
ERCC5
MGMT
NBN
PARP1
POLI
XPA
XRCC3
XRCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility.PMID 19116388Read ↗

Is there evidence of involvement of DNA repair polymorphisms in human cancer?Semantic proximity Read ↗

A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer.Semantic proximity Read ↗

Homologous Recombination Deficiency: Cancer Predispositions and Treatment Implications.Semantic proximity Read ↗

International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways.Semantic proximity Read ↗

Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.Semantic proximity Read ↗

Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.Semantic proximity Read ↗

Human DNA repair genesSemantic proximity Read ↗

Polymorphisms in DNA repair genes and associations with cancer risk.Semantic proximity Read ↗

Genomic landscape of DNA repair genes in cancerSemantic proximity Read ↗

Moderate-Risk Genes for Hereditary Ovarian Cancers Involved in the Homologous Recombination Repair Pathway.Semantic proximity Read ↗

DNA repair pathway genes and lung cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

Association Between Seven Selected Genetic Polymorphisms in DNA Repair-Related Genes and Breast Cancer Risk: Evidence from a Comprehensive Meta-analysis Including 96 Studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.