Article
Value of multilocus genetic risk score for atrial fibrillation in end-stage kidney disease patients in a Polish population.
Scientific reports - 18 Jun 2018
Saracyn Marek, Kisiel Bartłomiej, Bachta Artur, Franaszczyk Maria, Brodowska-Kania Dorota, Żmudzki Wawrzyniec, Szymański Konrad, Sokalski Antoni, Klatko Wiesław, Stopiński Marek, Grochowski Janusz, Papliński Marek, Goździk Zdzisław, Niemczyk Longin, Bober Barbara, Kołodziej Maciej, Tłustochowicz Witold, Kamiński Grzegorz, Płoski Rafał, Niemczyk Stanisław
Abstract excerpt
Genetic factors play a key role in the pathogenesis of atrial fibrillation (AF). We would like to establish an association between previously described single-nucleotide polymorphisms (SNPs) and AF in haemodialysed patients with end-stage kidney disease (ESKD-HD) as well as to assess the cumulative effect of all genotyped SNPs on AF risk. Sixteen SNPs were genotyped in 113 patients with AF-ESKD-HD and in 157...
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