Article
Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium.
PloS one - 1 Jan 2016
Norby Faye L, Eryd Samuel Adamsson, Niemeijer Maartje N, Rose Lynda M, Smith Albert V, Yin Xiaoyan, Agarwal Sunil K, Arking Dan E, Chasman Daniel L, Chen Lin Y, Eijgelsheim Mark, Engström Gunnar, Franco Oscar H, Heeringa Jan, Hindy George, Hofman Albert, Lutsey Pamela L, Magnani Jared W, McManus David D, Orho-Melander Marju, Pankow James S, Rukh Gull, Schulz Christina-Alexandra, Uitterlinden André G, Albert Christine M, Benjamin Emelia J, Gudnason Vilmundur, Smith J Gustav, Stricker Bruno H C, Alonso Alvaro
Abstract excerpt
BACKGROUND: Several studies have shown associations between blood lipid levels and the risk of atrial fibrillation (AF). To test the potential effect of blood lipids with AF risk, we assessed whether previously developed lipid gene scores, used as instrumental variables, are associated with the incidence of AF in 7 large cohorts. METHODS: We analyzed 64,901 individuals of European ancestry without previous AF at...
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