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Mutations in gyrA and gyrB in Moxifloxacin-Resistant Mycobacterium avium Complex and Mycobacterium abscessus Complex Clinical Isolates.

Antimicrobial agents and chemotherapy - 1 Sept 2018

Kim Su-Young, Jhun Byung Woo, Moon Seong Mi, Shin Sun Hye, Jeon Kyeongman, Kwon O Jung, Yoo In Young, Huh Hee Jae, Ki Chang-Seok, Lee Nam Yong, Shin Sung Jae, Daley Charles L, Suh Gee Young, Koh Won-Jung

Abstract excerpt

Data on the frequency of gyrA and gyrB mutations in fluoroquinolone-resistant isolates of the Mycobacterium avium complex (MAC) and the Mycobacterium abscessus complex (MABC) are limited. In our analysis, we did not find any resistance-associated mutations in gyrA or gyrB in 105 MAC or MABC clinical isolates, including 72 moxifloxacin-resistant isolates. Our findings suggest that mechanisms other than gyrA and...

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Identifiers

PMID: 29914959
DOI: 10.1128/AAC.00527-18
PMCID: PMC6125518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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