Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic basis of macrolide resistance in Mycobacterium avium isolated from patients with disseminated disease

1 Dec 1995

Abstract excerpt

Clarithromycin (CLM) and azithromycin (AZM) are important agents in the treatment of disseminated Mycobacterium avium complex disease; however, monotherapy with these macrolides often leads to clinically significant resistance. The underlying resistance mechanism was investigated by comparing 23S rRNA gene sequences in the domain V region of 10 CLM-susceptible strains included in this study. The only differences...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Mycobacterium research and diagnosis
Share to RNA and protein synthesis mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8592991
DOI: 10.1128/aac.39.12.2625

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic basis of macrolide resistance in Mycobacterium avium isolated from patients with disseminated diseasePMID 8592991Read ↗

Molecular mechanisms of clarithromycin resistance in Mycobacterium avium: observation of multiple 23S rDNA mutations in a clonal population.Semantic proximity Read ↗

Molecular basis of clarithromycin-resistance in Mycobacterium avium intracellulare complex.Semantic proximity Read ↗

Phenotypic drug-susceptibility profiles and genetic analysis based on whole-genome sequencing of Mycobacterium avium complex isolates in ThailandSemantic proximity Read ↗

Genetic basis for clarithromycin resistance among isolates of Mycobacterium chelonae and Mycobacterium abscessusSemantic proximity Read ↗

Clinical Characteristics, Treatment Outcomes, and Resistance Mutations Associated with Macrolide-Resistant Mycobacterium avium Complex Lung Disease.Semantic proximity Read ↗

Rapid detection of mutations associated with macrolide resistance in Mycobacterium avium complex.Semantic proximity Read ↗

The role of efflux pumps in macrolide resistance in Mycobacterium avium complexSemantic proximity Read ↗

Noncanonical mutations in ribosome nascent peptide exit tunnel confer clarithromycin resistance in Mycobacterium abscessus complex.Semantic proximity Read ↗

Development of a rapid detection method for the macrolide resistance gene in Mycobacterium avium using the amplification refractory mutation system-loop-mediated isothermal amplification method.Semantic proximity Read ↗

Antibiotic Susceptibility and Genotyping of Mycobacterium avium Strains That Cause Pulmonary and Disseminated Infection.Semantic proximity Read ↗

Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila.Semantic proximity Read ↗

Genetic basis of clarithromycin resistance in Bacillus anthracis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.