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Chromosomal mutations responsible for fluoroquinolone resistance in Ureaplasma species in the United States.

Antimicrobial agents and chemotherapy - 1 May 2012

Xiao Li, Crabb Donna M, Duffy Lynn B, Paralanov Vanya, Glass John I, Waites Ken B

Abstract excerpt

We sequenced the full lengths of the gyrA, gyrB, parC, and parE genes in 13 fluoroquinolone-resistant Ureaplasma isolates (levofloxacin MICs, 4 to 32 μg/ml) and 10 susceptible isolates (MICs ≤ 2 μg/ml). Mutations were detected in all resistant isolates but in none of the susceptible isolates. The most prevalent mutation was the S83L substitution in the ParC protein. No plasmid-mediated fluoroquinolone resistance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22371892
DOI: 10.1128/AAC.06342-11
PMCID: PMC3346621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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