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Article

Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A.

PloS one - 1 Jan 2013

Olsson Åkefeldt Selma, Maisse Carine, Belot Alexandre, Mazzorana Marlène, Salvatore Giulia, Bissay Nathalie, Jurdic Pierre, Aricò Maurizio, Rabourdin-Combe Chantal, Henter Jan-Inge, Delprat Christine

Abstract excerpt

Dendritic cells initiate adaptive immune responses, leading either to control cancer by effector T cells or to exacerbate cancer by regulatory T cells that inhibit IFN-γ-mediated Th1-type response. Dendritic cells can also induce Th17-type immunity, mediated by IL-17A. However, the controversial role of this cytokine in cancer requires further investigations. We generated dendritic cells from peripheral blood...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23441221
DOI: 10.1371/journal.pone.0056865
PMCID: PMC3575476

Genes

MCL1
CCL22
CXCL10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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