Article
PIK3CA mutation in gastric cancer and the role of microsatellite instability status in mutations of exons 9 and 20 of the PIK3CA gene.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jul 2018
Polom Karol, Marrelli Daniele, Roviello Giandomenico, Pascale Valeria, Voglino Costantino, Vindigni Carla, Generali Daniele, Roviello Franco
Abstract excerpt
BACKGROUND: A better understanding of molecular gastric cancer (GC) entities may help in tailored treatments of that neoplasm. The PIK3CA mutation is one of the most important in many cancers. OBJECTIVES: We performed a comparison of clinical and pathological data of the PIK3CA mutation in GC patients. MATERIAL AND METHODS: The analysis was done on 472 patients operated on in 1 center. Polymerase chain reaction...
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