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Article

The analysis of PIK3CA mutations in gastric carcinoma and metanalysis of literature suggest that exon-selectivity is a signature of cancer type.

Journal of experimental & clinical cancer research : CR - 16 Apr 2010

Barbi Stefano, Cataldo Ivana, De Manzoni Giovanni, Bersani Samantha, Lamba Simona, Mattuzzi Silvia, Bardelli Alberto, Scarpa Aldo

Abstract excerpt

BACKGROUND: PIK3CA is one of the genes most frequently mutated in human cancers and it is a potential target for personalized therapy. The aim of this study was to assess the frequency and type of PIK3CA mutations in gastric carcinoma and compare them with their clinical pathological correlates....

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Identifiers

PMID: 20398348
DOI: 10.1186/1756-9966-29-32
PMCID: PMC2865450

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20398348-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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