Physical activity and the risk of colorectal cancer in Lynch syndrome.

doi:10.1002/ijc.31611

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Article

Physical activity and the risk of colorectal cancer in Lynch syndrome.

International journal of cancer - 1 Nov 2018

Dashti S Ghazaleh, Win Aung Ko, Hardikar Sheetal S, Glombicki Stephen E, Mallenahalli Sheila, Thirumurthi Selvi, Peterson Susan K, You Y Nancy, Buchanan Daniel D, Figueiredo Jane C, Campbell Peter T, Gallinger Steven, Newcomb Polly A, Potter John D, Lindor Noralane M, Le Marchand Loic, Haile Robert W, Hopper John L, Jenkins Mark A, Basen-Engquist Karen M, Lynch Patrick M, Pande Mala

Abstract excerpt

Greater physical activity is associated with a decrease in risk of colorectal cancer for the general population; however, little is known about its relationship with colorectal cancer risk in people with Lynch syndrome, carriers of inherited pathogenic mutations in genes affecting DNA mismatch repair (MMR). We studied a cohort of 2,042 MMR gene mutations carriers (n = 807, diagnosed with colorectal cancer), from...

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PMID: 29904935
DOI: 10.1002/ijc.31611
PMCID: PMC6195467

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