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Article

Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP).

PloS one - 5 Apr 2011

Hughes Laura A E, Simons Colinda C J M, van den Brandt Piet A, Goldbohm R Alexandra, de Goeij Anton F, de Bruïne Adriaan P, van Engeland Manon, Weijenberg Matty P

Abstract excerpt

BACKGROUND: We investigated how body size and physical activity influence the risk of the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). METHODS: In the Netherlands Cohort Study (n = 120,852), risk factors were self-reported at baseline in 1986. After 7.3 years of follow-up, 603 cases and 4,631 sub-cohort members were available. CIMP status according to the Weisenberger markers was determined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21483668
DOI: 10.1371/journal.pone.0018571
PMCID: PMC3071697

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