Article

Sex-based differences in circulating microRNA and metabolite signatures associated with physical activity in Lynch Syndrome carriers

2025-09-30

Abstract excerpt

<title>Abstract</title> <p>Lynch syndrome carriers face a high cancer risk, especially for colorectal cancer. Although physical activity is known to lower cancer risk in Lynch syndrome, it remains unclear whether this protective effect is the same between sexes. We used an integrated omics approach to examine molecular mechanisms associated with physical activity in Lynch syndrome, focusing on sex-specific differ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cb886dd8-10d9-59f8-9754-290132bfbea8
DOI: 10.21203/rs.3.rs-7432623/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sex-based differences in circulating microRNA and metabolite signatures associated with physical activity in Lynch Syndrome carriersDOI 10.21203/rs.3.rs-7432623/v1Read

Circulating metabolome landscape in Lynch SyndromeSemantic proximity Read

Modifiable risk factors for cancer among people with lynch syndrome: an international, cross-sectional surveySemantic proximity Read

Multi-omics Approaches to Uncover Liquid-Based Cancer-Predicting Biomarkers in Lynch SyndromeSemantic proximity Read

Physical activity and the risk of colorectal cancer in Lynch syndrome.Semantic proximity Read

Characterization of methylation patterns associated with lifestyle factors and vitamin D supplementation in a healthy elderly cohort from Southwest SwedenSemantic proximity Read

Physical activity and molecular subtypes of colorectal cancer: a pooled observational analysis and Mendelian randomization study.Semantic proximity Read

Circulating Metabolite Signatures Linking Physical Activity to Inflammatory Bowel Disease Risk and Interactions With Genetic Susceptibility.Semantic proximity Read

miRNA-based “Fitness Score” to Assess the Individual Response to Diet, Metabolism and ExerciseSemantic proximity Read

Circulating MicroRNAs as Potential Biomarkers of Exercise ResponseSemantic proximity Read

A transcript-wide association study in physical activity intervention implicates molecular pathways in chronic diseaseSemantic proximity Read

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.Semantic proximity Read

The influence of Sex on microRNA expression in Human Skeletal MuscleSemantic proximity Read