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T Cells Prevent Hemorrhagic Transformation in Ischemic Stroke by P-Selectin Binding.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2018

Salas-Perdomo Angélica, Miró-Mur Francesc, Urra Xabier, Justicia Carles, Gallizioli Mattia, Zhao Yashu, Brait Vanessa H, Laredo Carlos, Tudela Raúl, Hidalgo Andrés, Chamorro Ángel, Planas Anna M

Abstract excerpt

Objective- Hemorrhagic transformation is a serious complication of ischemic stroke after recanalization therapies. This study aims to identify mechanisms underlying hemorrhagic transformation after cerebral ischemia/reperfusion. Approach and Results- We used wild-type mice and Selplg-/- and Fut7-/- mice defective in P-selectin binding and lymphopenic Rag2-/- mice. We induced 30-minute or 45-minute ischemia by...

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Identifiers

PMID: 29903733
DOI: 10.1161/ATVBAHA.118.311284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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